OUR SCIENCE & PLATFORM
Get the right one
When facing complex problems, we need to have a full understanding and analysis of the subject itself in order to find a good solution. This unique understanding and analysis will guide us to think in the right direction. When the direction is right, if you happen to have the right tools, it will be closer to solving the problem.
Unique understanding of the immune system
The immune system is like a complex network of immune cells and molecules. It has two regulatory mechanisms, activation and inhibition, and is balanced in a healthy state. How to rebalance the unbalanced immune system is a challenging task. Although the rule of life operation cannot be calculated and predicted by formula like launching rockets or synthetic plastic products for the time being, fortunately, a large number of scientific studies have proved the physiological functions of many immune cells and molecules. On the basis of these research results, each researcher will have different understanding and analysis. Our team also has our own understanding and analysis. It is these unique insights that guide our research and help us gradually make some interesting discoveries.
Local Accumulation Screen System
Efficacy evaluation tech is an essential tool for drug screening. The Local Accumulation Screen System (LASS) designed by the team played a great role in the discovery of KN330. Expressing the molecules to be evaluated in the local tumor, the drug is highly enriched in the local area of the focus, and the best curative effect of each evaluated molecule can be presented intuitively. At the same time, due to the high concentration of drugs, it can avoid the false negative related to evaluation failure caused by the toxicity of large doses. For there is no need to express and purify proteins ex vivo, the platform also reduces greatly the workload of evaluation.
Other platforms
Evaluation and screening platform for drugs related to autoimmune diseases is not disclosed.
Pipelines
About us
The team
Knockgene was founded by several highly creative scientists from China. The main office locates in Beijing. The team believes that de novo designed drug can treat diseases better. With our unique insights into the immune system and the innovative drug screening platform, we have made some interesting discoveries in the field of immune related diseases. We look forward to finding more drugs with excellent efficacy and reliable safety.
Our mission
The team is committed to developing the first in class immunotherapeutic drugs. The company is established to the development and improvement of the drugs in the companion animal market.
Investment & Cooperation
If you want to invest, patent licensing, joint development cooperation, welcome!